Nutritional value of it

Although Poria is a medicinal material, the content of nutrients in Poria is also very rich. Proper consumption of Poria can not only help us to supplement a lot of organic nutrients such as polysaccharides, glucose, protein, amino acids, organic acids, etc. It can also play a good role in supplementing potassium salts.

In addition, regular consumption of Poria Cocos Extract is also very helpful to help us all strengthen the immune function of the body. In addition, if you take some tuckahoe properly, it can also play a good anti-tumor effect and diuretic effect, which is helpful for all of us to protect the liver. The effect is also very good.

Poria cocos sclerotium extract can also effectively inhibit the occurrence of ulcers, and the effect of preventing and treating hypoglycemic, anti-radiation and other diseases is also very good.

Application experiment of Poria cocos extract

Poria cocos extract improves functional dyspepsia by regulating brain-gut peptides, immunity, and repairing gastrointestinal mucosa

Objective: To investigate the therapeutic effect and mechanism of Poria cocos and its three extracts (triterpenoids, PCT; water-soluble polysaccharides, PCWP; acid polysaccharides, PCAP) on FD in rats, so as to explore the active substances of PC extracts in the treatment of FD, make full use of its medical value.

Methods: The chemical constituents of PC extracts were analyzed and quantified by ultra-high performance liquid chromatography quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) and gel permeation chromatography (GPC/SEC).

The FD rat model was established by weight-bearing forced swimming and fasting every other day for 42 days. 70 Wistar rats were divided into a control group, model group, Buzhong Yiqi pill group, PCD group (Poria decoction), PCT group, PCWP group, and PCAP group. After 14 days of treatment, the effects and mechanisms were observed by ELISA, histopathology, immunohistochemistry, and Western blot.

RESULTS: A total of 77 triterpenoids were identified. PCWP is mainly composed of A component (Mw: 3.831 × 107 Da), B component (Mw: 5.650 × 106 Da), and C component (Mw: 113117 Da). PCAP is a homogeneous component with an average molecular weight of 74320 Da. PCT, PCWP, and PCAP all relieve FD symptoms. Compared with the control group, there was no significant difference in the organ indices of the heart, kidney, liver, lung, stomach, and small intestine, and the spleen and thymus indices were significantly decreased in the model group. Compared with the model group, the serum levels of D-xylose, ACh, ALB, and TP in the BZYQP, PCD, and PCAP groups were significantly or extremely significantly increased.

What is Poria Cocos Extract?

Poria cocos powder is a kind of medicinal material. Poria is rich in nutrients, and regular consumption can enhance the immune function of the body, protect the digestive system, antibacterial, puzzle, and other effects and functions. Poria cocos is the dried sclerotia of Poria cocos (Schw.) Wolf of the family Poriaaceae, parasitic on the rhizomes of Pinaceae or Pinus massoniana, buried 20-30 cm under the soil to multiply. The inner part of Poria core is Poria cocos, the outer part is Poria bark and the sclerotia with pine roots is Poria God. Poria is a fungus of the Poriaaceae family, and the skin of Poria is the dried epidermis peeled off during processing of the sclerotia of Poria. As a traditional medicine and food homologous product, Poria has a long history of application.

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Function

1. Diuretic effects.

Poria cocos has a diuretic effect, which can promote the excretion of electrolytes such as sodium, chloride and potassium, thereby inhibiting the repeated absorption of renal tubules, helping to eliminate edema, and helping to strengthen the kidneys.

2. Improve immunity

Poria mushroom extract contains a large number of polysaccharides that are easily absorbed by the human body, which can improve human immunity, prevent diseases and delay aging. It is very suitable for people who are chronically ill and weak. In addition, people who rarely bask in the sun on weekdays can also eat Poria to make up for the low immune function caused by insufficient sunlight.

3. Protect the digestive system

Some scholars have done experiments and found that the Poria cocos extract has obvious protective effect on the liver injury of rats caused by CCl4, which can significantly reduce the activity of alanine aminotransferase and prevent liver cell necrosis. In addition, some studies have found that Poria has a direct relaxation effect on the isolated intestine of rabbits, has a preventive effect on ulcers formed by pyloric ligation in rats, and can reduce gastric acid.

4. Antibacterial effect

Poria cocos extract contains antibacterial and anti-inflammatory components, which have inhibitory effects on Staphylococcus aureus, Escherichia coli and Proteus.

5. Puzzle and brain

The choline contained in Poria cocos can enhance and improve brain memory function and has intellectual pharmacological effects.

6. Invigorating the spleen and invigorating the spleen

The medicinal effect of Poria cocos is not very strong, it belongs to the very bland kind, and long-term use of Poria cocos will not harm the body. The reabsorption function can be improved by taking Poria cocos when urination is not smooth and edema usually occurs. Poria can also strengthen the spleen and invigorate the spleen, and has the effect of invigorating the spleen and replenishing the spleen for those who are thin, inappetence, and occasionally feel weak and weak in the spleen.

7. Improve physical fitness and improve immunity

Poria contains a lot of polysaccharide substances that are easily absorbed by the human body, which can improve the body's immunity, increase the cytotoxicity of T lymphocytes, prevent diseases, and delay aging.

Poria can be taken to improve the immune function caused by insufficient sunlight, so as to improve the physical quality, increase the immune function of the body, and prevent some cancer cells from invading the body.

8. Antibacterial and dehumidifying

Poria cocos extract contains antibacterial ingredients, which have inhibitory effects on common Staphylococcus aureus, Escherichia coli and Proteus. If there is too much phlegm due to heavy dampness and symptoms of shoulder and back pain, you can eat some Poria cocos to play a good role in removing dampness. For patients with palpitations and insomnia, Poria can be used to calm the mind. It can promote sleep and improve restlessness.

10. Immunomodulation

The immunomodulatory function of Poria cocos is currently the most recognized function, and there are many studies on this aspect. For example, the identification of ingredients and in vitro animal cell experiments with Poria cocos extracts showed that the 2-N-acetylamino-D-glucose and 6-0-α-D-mannose-D-glucose contained in it have enhanced The biological activity of immunity can promote the proliferation of lymphocytes in mice, and triterpenoids have a two-way immune regulation function. From the components of the Poria cocos extract, the T and B lymphocyte proliferation model was used as the screening platform, the lymphocytes were used as the target, the cell survival rate was determined by the live cell detection method, and the components with immunomodulatory function were screened. Degradation products, carboxymethylated derivatives and Poria cocos ethyl acetate extract were the main effective parts. And further component identification and immune function research results showed that the four compounds such as pachylic acid have immunosuppressive biological activity. How to improve the immune regulation function of Poria cocos is also a current research aspect. The content of water-soluble polysaccharides in Poria cocos extract is low, which limits its biological function. Therefore, Poria polysaccharides are subjected to certain structural modifications, such as carboxymethylation, sulfate esterification, hydroxypropylation, hydroxyethylation Various derivatives of Poria cocos polysaccharide can be obtained by synthesizing, methylating, etc., and improving its water solubility and biological activity to varying degrees.

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