What is Sophora Flavescens Extract?
Sophora Flavescens Root Extract is a substance extracted from the Sophora japonica plant, Sophora flavescens. Sophora flavescens has the functions of clearing heat, dehumidification, insecticide, and diuresis. It usually grows in plains, hillside meadows, roadsides, red soil, and sand The texture of a sunny place.
The root of It is tough, the cross-section is coarse and fibrous, and the color is yellow-white. It has a mild gas and a very bitter taste. It has antibacterial, anti-inflammatory, anti-acne, whitening, and other effects. It has been used for beauty and skincare as early as hundreds of years ago, and now it is a type of cosmetic raw material favored by major cosmeceuticals.
The main chemical components are alkaloids and flavonoids. It is a natural antibacterial agent, which is blended with viscose spinning solution to make fibers, which can not only retain the good wearing performance of viscose fibers but also have certain antibacterial properties. A safe dose is 45-90mg per day. It mainly has cosmetic skin care, anti-inflammatory and whitening effects. It is cold in nature and has the effects of clearing heat and dampness and killing insects. The use bath can kill insects and relieve itching, clear the dampness and heat of lower Jiao, and relieve skin itching problems. It can balance oil secretion, dredge, Astringent pores, remove toxins and impurities inside the skin, and use its rich herbal nutrition to promote the growth and repair of damaged blood vessels and nerve cells, restore the vitality of subcutaneous capillary cells, restore firmness and smoothness to the skin, and play a role in beauty and skin care. ; Total alkaloids and oxymatrine have obvious whitening effects, and have obvious therapeutic effects on leukopenia caused by cyclophosphamide, X-ray, and cobalt ray irradiation; Swelling, increased peritoneal exudation in mice caused by acetic acid, and carrageenan footpad swelling in rats, all have inhibitory effects.
Quality Control COA
ITEM | STANDARD | TEST RESULT | TEST METHOD |
Assay | 98% | HPLC | HPLC |
Physical & Chemical | |||
Appearance | White Powder | Complies | Visual |
Odor & Taste | Characteristic | Complies | Organoleptic |
Particle Size | 98% Pass 80 mesh | Complies | USP<786> |
Loss on drying | ≤5.0% | 2.06% | USP<731> |
Ash | ≤5.0% | 2.38% | USP<281> |
Heavy Metal | |||
Pb | ≤2.0ppm | 0.230ppm | ICP-MS |
As | ≤2.0ppm | 0.015ppm | ICP-MS |
Cd | ≤1.0ppm | 0.038ppm | ICP-MS |
Hg | ≤0.5ppm | 0.072ppm | ICP-MS |
Microbiological Test | |||
Total Plate Count | ≤1,000cfu/g | 316cfu/g | AOAC |
Yeast and Mould | ≤100cfu/g | 42cfu/g | AOAC |
E.Coil | Negative | Negative | AOAC |
Salmonella | Negative | Negative | AOAC |
Function
1. Protect the gastric mucosa
Ku Shen Extract has an obvious protective effect on gastric mucosal damage caused by hydrochloric acid, ethanol, and indomethacin, and its main components are flavanones. Recent studies have shown that matrine is also one of the effective components of Sophora flavescens to resist gastric mucosal damage. It has obvious effects on gastric mucosal damage caused by stress, hydrochloric acid, ethanol, and indomethacin in rats. Protective effects. It indicates that Sophora flavescens may have a certain anti-ulcer effect.
2. Anti-inflammatory effect
Matrine has obvious anti-inflammatory effects on acute exudative inflammation caused by various pro-inflammatory agents (croton oil, glacial acetic acid, carrageenan, egg white), and is similar to hydrocortisone. Its anti-inflammatory mechanism has nothing to do with the pituitary-adrenal cortex system, and matrine still has a significant anti-inflammatory effect on adrenalectomy mice. Studies have shown that this product has non-steroidal anti-inflammatory drug properties. In addition, matrine has a stabilizing effect on erythrocyte membrane, and drugs that have a stabilizing effect on erythrocyte often have a stabilizing effect on lysosomal membrane, thereby reducing the release of inflammatory mediators and achieving anti-inflammatory purposes.
3. The effect of increasing white blood cells
Oxymatrine can prevent mouse leukopenia caused by MMC and cyclophosphamide. Intravenous or intramuscular injection of total matrine and oxymatrine can significantly increase the number of peripheral blood white blood cells in normal rabbits , and the effective time, maintenance time and peak white blood cell count of oxymatrine on the whitening effect of normal rabbits are basically the same as those of total alkaloids within 18 days after administration, and the whitening effect is better than that of shark liver. alcohol.
4. Effects on the cardiovascular system
Intravenous injection of matrine and oxymatrine significantly antagonized aconitine- and chloroform-adrenaline-induced arrhythmias in rats; intraperitoneal injection significantly antagonized chloroform-induced ventricular fibrillation in mice and also increased aconitine-induced arrhythmias in rats The required dose is used to fight against barium chloride-induced arrhythmia in rats and arrhythmia induced by ligation of the anterior descending coronary artery in rats.
5. Asthma and expectorant effect
Matrine mainly produces anti-asthmatic effects by excitating beta receptors, especially excitatory central beta receptors, relieving bronchospasm and inhibiting the release of antibodies and slow-reacting substances.
6. Stabilizing effect
Total matrine can significantly inhibit the free activities of mice; significantly inhibit the passive activities of mice; high doses can inhibit the fighting and aggressive behavior of lonely mice.
Application
It can be used in medicine.
Sophora Root Powder is a kind of traditional Chinese medicine. It is an ingredient directly extracted from the plant Sophora flavescens. It is also a pure natural ingredient. After consumers and patients take it, it will not cause irritation and damage to the body but can cure various diseases of the body.
Since the root is very tough and contains a lot of crude fiber, it is a yellow-white product directly extracted from the root. It has a weak smell and a very bitter taste. Many years ago It was used in beauty and skincare. It can be made into a variety of cosmetics and applied to the skin. It has the effect of killing insects, bacteria, and viruses stored in the skin, and can also eliminate inflammation in the skin. Effective Improves skin itching caused by mosquito bites, can also balance oil, reduce oil secretion, effectively unclog pores, improve large pores, and can also remove impurities and makeup residues in the skin, making pores cleaner. Some women can also promote capillary circulation on the surface of the skin after use, which can improve the problems of acne and acne caused by poor blood circulation, and can also restore damaged cells, making the skin firmer and more elastic. Secondly, it has an anti-inflammatory effect. Clinical experiments show that after using it, it can inhibit the verification of the body, improve the symptoms of getting angry, and can also treat the symptoms of yellow urine.
What are the benefits and uses of Sophora Radix Extract? In the process of use, it is mainly used in medicine, and can also resist the growth and spread of cancer cells and tumor cells in the body, effectively reducing the toxic and side effects of radiotherapy and chemotherapy on the body.
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