Fenugreek Seed Extract Powder

Pharmacological effects of fenugreek extract

The first is that Fenugreek Seed Extract has the effect of lowering blood pressure. For patients with three high diseases, after taking it, it can lower blood pressure, lower blood sugar, and blood lipids, prevent the occurrence of three high diseases, and have a good therapeutic effect on the symptoms of diabetes. Some patients can have a strong protective effect on the liver after taking it, effectively reducing the toxins deposited in the liver, and preventing the recurrence of liver diseases. Secondly, it has the ability to treat ulcerative diseases. It has a good therapeutic effect on the symptoms of gastric ulcers and oral ulcers. It can also remove free radicals in the body, and can also improve the antioxidants of the gastrointestinal mucosa, and can also reduce the symptoms of mucosal damage. For patients with cancer and tumor diseases, after taking it, it can inhibit the growth and spread of tumors and cancer cells in the body, and can also reduce the toxic side effects of radiotherapy and chemotherapy on the body. Also, for adult men, after taking it, it has the effect of strengthening the yang and nourishing the kidney, which can improve the symptoms of premature ejaculation and impotence caused by kidney deficiency, and can also enhance the male's own sexual life ability, and can also improve the symptoms of low libido in men. Some adult men insist on taking it for a period of time, which can improve the diseases caused by endocrine imbalance.

Fenugreek extract has many pharmacological effects. First of all, it can lower blood pressure, and it can also treat type 2 diabetes. It also has the effect of invigorating the kidney and relieving itching. In addition, it has the effect of protecting the kidney. In clinical aspect, it can also be used to treat chronic renal failure, which is very effective. It can also lower blood sugar levels, regulate blood lipids and help lose weight. It can also prevent or treat fatty liver problems, and is also good for liver health. Fenugreek extract can play an anti-ulcer effect, especially for the treatment of gastric ulcer, it can inhibit the secretion of gastric acid, and can also improve the antioxidant capacity of gastric mucosa and reduce the damage of gastric mucosa. It also has anti-tumor effect, especially for the adjuvant therapy of leukemia. The effect is good. It also has a good adjuvant therapy effect for acute or chronic chemical liver injury, which can protect the liver and brain cells. It can improve the fluidity of blood, as well as microcirculation. It also has the effect of invigorating the kidney and strengthening yang, which can improve sexual performance.

What is Fenugreek Seed Extract Powder？

As early as more than 2,000 years ago, residents of West Asia, the Middle East, and Arab countries have begun to eat fenugreek as a wild vegetable. It mainly promotes the development of female breasts and the growth of breast tissue, so it is also called "milk grass". It is of great help in relieving menopausal symptoms and improving premenstrual syndrome. In India and Arab countries, fenugreek is commonly used by folk physicians as a tonic, aphrodisiac, analgesic, oral cooling agent, and amenorrhea. In some Arab countries in the Middle East, it is also often used in mothers with less milk as a natural catalyst to increase milk secretion.

The preparation method of fenugreek extract is mainly as follows: sun-drying fenugreek seeds, pulverizing and decocting with distilled water to dissolve the active ingredients in water, and preparing an extract, which is obtained by processes such as concentration under reduced pressure, filtration, and separation. Ultrafiltration and nanofiltration membranes can be used to extract effective substances from Fenugreek, which can make the effective ingredients reach the required concentration, thereby preparing high-quality fenugreek extracts. The application research of fenugreek extract is still in-depth. Trigonella Foenum Graecum Seed Extract can increase serum testosterone concentration, reduce body fat, and increase muscle mass, thereby improving physical fitness. It can be used to produce dietary additives and functional foods for exercisers. In addition, fenugreek extract can be used to treat intractable constipation, promote maternal milk secretion, and can also be used for weight loss. In 2019, Nutriconnect launched andropique, a fenugreek extract product designed for athletes, which was approved for sale in Canada and India that year.

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Function

1. Lowering blood pressure

4-Hydroxyisoleucine is isolated from fenugreek seeds, which has a therapeutic effect on type 2 diabetes. Fenugreek has the effects of nourishing yang, lowering blood sugar, and lowering blood lipids, which may be related to the amino acids mentioned above.

2. Kidney protection

Fenugreek Extract can reduce serum urea nitrogen and creatinine levels in rats with renal failure. Clinical use of fenugreek decoction is effective in the treatment of chronic renal failure.

3. Anti-ulcer effect

Studies have shown that the water extract of fenugreek seeds and the gel fraction isolated from the seeds have significant anti-ulcer activity. This effect is not only due to its inhibitory effect on gastric acid secretion but also has a certain effect on gastric mucosal glycoprotein. The water extract of fenugreek seeds prevents alcohol-induced lipid peroxidation by improving the antioxidant capacity of gastric mucosa, thereby reducing mucosal damage.

4. Anti-tumor effect

The papain contained in fenugreek seeds has significant activity against lymphoid leukemia. Trigonelline contained in the seeds can prolong the life of leukemia P388 mice by 31% at the level of 12.5mg·kg-1 and has a significant inhibitory effect on mouse liver cancer. The water extract of fenugreek seeds was administered by subcutaneous injection to mice inoculated with Ehrlich ascites before and after inoculation, and the results showed that the inhibition rate of cancer cell growth was more than 70%. Quantitative analysis of mouse peritoneal effluent (secretory fluid) cells and macrophages showed increased results.

5. Liver protection

The water extract of fenugreek was administered to the mouse model of acute liver injury caused by carbon tetrachloride and D-galactosamine, and the effects of administration at different times and doses before and after exposure to the mice were observed. The lipid peroxidation level was also observed. The results showed that fenugreek extract could effectively inhibit the elevation of serum ALT and AST in mice with acute liver injury, showing a good dose-response relationship. Fenugreek water extract has a protective effect on the liver of rats with chronic liver injury induced by carbon tetrachloride.

6. Lowering blood lipids

Methanolic extract of the defatted portion of fenugreek seeds significantly reduces serum cholesterol levels in normal dogs. Its total extract also has a lowering effect on serum total cholesterol in diabetic hyperlipidemic dogs. The trigonelline contained in fenugreek seeds can reduce the content of total cholesterol and free cholesterol in the plasma of mice.

7. Protective effect on cerebral ischemia

The study showed that the total saponins of fenugreek significantly prolonged the average survival and wheezing time of severe cerebral ischemia in mice with acute incomplete cerebral ischemia, suggesting that the drug has a protective effect on cerebral ischemia injury. Total fenugreek saponins can prolong the coagulation time of mice, inhibit the platelet aggregation rate of rabbits, reduce blood viscosity, and improve blood fluidity and microcirculation. 8. The results of invigorating the kidney and strengthening the yang indicate that the material basis of the effect of fenugreek for strengthening the kidney and strengthening yang is the high content of zinc and manganese in the seeds. According to research, the content of zinc and manganese in kidney-tonifying Chinese medicine is high. If the body lacks zinc and manganese, it will lead to low endocrine function and gland atrophy, which will reduce endocrine hormones, slow growth, gonadal degeneration, and sexual dysfunction.

9. Improve learning and memory impairment

Studies have shown that the total saponins of fenugreek at 40, 80, and 160 mg·kg-1 can antagonize the memory acquisition impairment caused by scopolamine; improve the memory consolidation defect caused by the sodium nitrite protein synthesis inhibitor, and also have the effect of resisting the memory impairment effect of ethanol. , indicating that fenugreek contains active ingredients that promote protein synthesis; it has the effect of improving learning and memory disorders. Lecithin, one of the active ingredients in fenugreek seeds, can improve neurological dysfunction and disorders, restore brain function, enhance memory, and resist aging.

10. Anti-inflammatory and slimming effects

Fenugreek seed extract contains steroidal saponins with diuretic and anti-inflammatory activities. Long-term use of fenugreek gum (mixed with various foods) has a better weight loss function for obesity.

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